Adrafinil. What is it and what does it do?

The Razor's EdgeEver since the movie Limitless, companies have been marketing products claiming to be “The” NZT 48.  Well…. they’re not, but some may come close.  So what is Adrafinil and what does it do?  Right off the bat this is a prodrug that metabolizes in the liver to primarily Modafinil which promotes wakefulness and alertness. In the U.S a prescription is needed for Modafinil but not for Adrafinil.  It is thought Modafinil inhibits re-uptake of the dopamine transporter which will result in larger extracellular concentrations of dopamine.   It does take some time before you will feel any effects because it needs to accumulate in the bloodstream, approx. 45 minutes to an hour.  Adrafinil has a half-life of 10 – 12 hours so do not take it if you plan on sleeping within that time-frame.  The effects are not strong, so don’t expect the same feeling as taking your pre-workout or double shot of expresso, but you will notice an increase in overall energy.  Your focus will increase, productivity will increase, and you will not be tired for quite some time.  As for being the same as NZT 48, not even close, but some studies show Phenylpiracetam to have memory enhancement effects so stacking them will get you as close to the “real thing” as scientifically possible in todays world.  Blackstone Labs The Razor’s Edge has already done this for you and added CDP Choline for even greater learning and memory retention.

Modafinil has been approved for certain use by astronauts aboard the International Space Station, and even the US Air Force.  The World Anti-Doping Agency added Adrafinil and Modafinil as a prohibited stimulant because it has been shown to extend the amount of time it takes to reach exhaustion and reduce the perception of effort required to sustain.  Also a very important precaution, do not combine this with yohimbine as this may cause a dangerous increase in blood pressure and heart rate.  Some side effects may be stomach pain, skin irritation, anxiety and elevated liver enzymes with prolonged use.