L-Carnitine

L-Carnitine

L-carnitine supplements are one of the supplements gaining popularity in recent years as the fitness and sport industries conquer the new territory of more and more ‘civilians’. Since it’s become popular for everyone from physical workers to office rats to be fit and nutrakey-acetyl-l-carnitine-250g-supplement-centralspend most of their time in the gym or fitness studio, supplements such as l-carnitine have been in their prime. But what is it, what are the uses and side effects and is it worth the money?

The science behind it

L-carnitine is an amino acid –like and vitamin-like substance related to the B vitamin group. It used to be referred to as vitamin BT. It is a compound which helps transport fatty acids from the blood into the mitochondria so that they can be used as energy. L- carnitine is important for energy and metabolism of fats. If you want to utilize fat effectively or take even more advantage of your fat ‘melting away’ during exercise – l-carnitine is your guy. It has also been found to reduce fatigue which will help you stay active and make your workouts more intense.

The benefits

  • Fat burning – of course the primary function is fat metabolism and turning fat cells into energy by oxidizing them. Supplementation with l-carnitine is very helpful during weight loss.
  • Muscle Mass Increase-  Since it increases endurance and strength- it promotes lean muscle mass growth
  • Bone Mass Retention- Studies show that L-Carnitine decreases bone loss associated with old age.
  • Heart Condition Prevention – is often used alongside heart medicine for heart conditions and in people who have suffer heart attacks.
  • Kidney Treatment – your kidneys produce carnitine, so in kidney diseases it is also often used as treatment
  • Infertility – according to research, l-carnitine can help improve both sperm count and quality of sperm
  • Type II Diabetes Prevention – regulates metabolism increasing glucose oxidation, glucose storage, as well as glucose uptake
  • Support of the Immune System – l- carnitine is an antioxidant, it protects us from free radicals doing damage to our cells. Will support your immune system and protect you from health issues starting with the common cold all the way to life-threatening diseases
  • Improved Brain Function – as we age, cognitive function decreases. L-carnitine supports healthy brain function especially in seniors

 

Side Effects

Does it all sound too good to be true? L-carnitine supplements have been shown to cause a few side effects, a high dose can cause nausea, abdominal cramps, vomiting, and diarrhea.

A positive ‘side effect’ is an unexpected one and not related to fitness so much. One study from Italy has shown that l-carnitine was more effective than testosterone therapy for treating male erectile dysfunction and infertility. There are two reasons for this – firstly, it increases blood circulation and vascularity and secondly it improves the quality of the sperm.

Our Judgment: It’s worth a try

 

To conclude, l-carnitine has been tested enough to prove it does work and it’s safe. Therefore, it’s worth a try, especially if you are serious about your gym progress. Before you consume any supplement, research the proper dosage and possible interactions (with medicine you take and/or other supplements).

*It is recommended to take l-carnitine with carbs which spike insulin and enhance muscular uptake.

 

 

 

 

Adrafinil. What is it and what does it do?

The Razor's EdgeEver since the movie Limitless, companies have been marketing products claiming to be “The” NZT 48.  Well…. they’re not, but some may come close.  So what is Adrafinil and what does it do?  Right off the bat this is a prodrug that metabolizes in the liver to primarily Modafinil which promotes wakefulness and alertness. In the U.S a prescription is needed for Modafinil but not for Adrafinil.  It is thought Modafinil inhibits re-uptake of the dopamine transporter which will result in larger extracellular concentrations of dopamine.   It does take some time before you will feel any effects because it needs to accumulate in the bloodstream, approx. 45 minutes to an hour.  Adrafinil has a half-life of 10 – 12 hours so do not take it if you plan on sleeping within that time-frame.  The effects are not strong, so don’t expect the same feeling as taking your pre-workout or double shot of expresso, but you will notice an increase in overall energy.  Your focus will increase, productivity will increase, and you will not be tired for quite some time.  As for being the same as NZT 48, not even close, but some studies show Phenylpiracetam to have memory enhancement effects so stacking them will get you as close to the “real thing” as scientifically possible in todays world.  Blackstone Labs The Razor’s Edge has already done this for you and added CDP Choline for even greater learning and memory retention.

Modafinil has been approved for certain use by astronauts aboard the International Space Station, and even the US Air Force.  The World Anti-Doping Agency added Adrafinil and Modafinil as a prohibited stimulant because it has been shown to extend the amount of time it takes to reach exhaustion and reduce the perception of effort required to sustain.  Also a very important precaution, do not combine this with yohimbine as this may cause a dangerous increase in blood pressure and heart rate.  Some side effects may be stomach pain, skin irritation, anxiety and elevated liver enzymes with prolonged use.

What is Ibutamoren (MK-677)?

There has been some buzz on this relatively new supplement compound Ibutamoren also known as MK-677, but what exactly is it and what can it do for you?

Well MK-677’s main purpose is to aid in the bodies recovery and help add lean muscle mass by increasing growth hormone levels. MK-677 is a growth hormone secretagogue which triggers the pituitary gland thus increasing the levels of growth hormone.  Some studies have been done showing increases by up to 90%, which is absolutely amazing! Normal dosing per day has been around 10-25 mg with dose dependent results.  Most people will see faster recovery times, increased lean muscle mass, decreased body fat and quicker healing times when injured.   There are some side effects though such as numb extremities and mild lethargy. As with any dietary supplement caution should be used especially when on medication. You can find MK-677 in Blackstone Labs MK Ultra which is dosed at 10 mg per capsule.

 

FDA Issues Warning Letter to 14 Companies Regarding Amp-Citrate, DMBA

AMP Citrate Products - SupplementCentral.com

Here we go again!  The FDA just issued 14 warning letters to Supplement Companies that have DMBA in their products claiming the ingredient is not a legal dietary supplement and products that contain it are considered to be adulterated. Amp-Citrate also known as 1,3-Dimethylbutylamine; 4-Amino Methylpentane Citrate; AMP; 4-Amino-2 Methylpentane Citrate is a similar ingredient to DMAA which has already been pulled voluntarily by many companies.  A few of the companies that were issued warning letters are Blackstone Labs, Nutrex Research, Prime Nutrition, Lecheek Nutrition and VPX Sports.

AMP Citrate & DMAA Chart - Chemical Compounds - SupplementCentral.com

What does this mean?  Well the supplement companies have 15 business days to respond and most likely the product will cease production during this time. Meaning, there will be no more product(s) produced containing AMP Citrate.

Now what does this mean to you?  Well if you are a AMP Citrate or an old DMAA junky then we suggest you start stocking up on these items, as supplies will quickly diminish if the FDA starts to force their hand.

 

Perform at your highest level with Sustamine™

Many companies are jumping on the Sutamine™ (l-alanyl-l-glutamine) wagon but many consumers know little about it. Sutamine™ had been introduced to the industry in the early parts of 2010, with a quick action in placing the compound into supplement formulations. The real question is, what is it?

The basics of Sustamine™ is that it is an ingredient that has scientifically proved to help hydrate the body and sustain energy during exercise or exertion.* It has been said to enhance water and electrolyte absorption during hydration process, stimulate glycogen synthesis*, inhibit muscle protein breakdown*, promote muscle protein synthesis, and stimulate the immune system*.

It has been shown in studies by the Institute of Exercise Physiology and Wellness, University of Central Florida that Sustamine™ has shown a large increase in cognitive response when consuming Sustamine™ than the participants that consumed nothing and those who consumed a sports electrolyte drink, not containing Sustamine™.

What makes this compound that much better than regular L-Glutamine?

The compound Sustamine™ is a set; Dipeptides: L-Alanyl-L-Glutamine. Dipeptides are whole proteins important for providing amino acids. A dipeptide is the most efficient form of protein for absorption. Dipeptides are processed and accepted by specific transporters that are located in the gut surface. The key to the dipeptide is for the body to absorb the l-glutamine compound more effectively.

USPlabs Modern BCAA+ - Sustamine

The first part of the Sustamine™ compound is l-alanine. Alanine is categorized as a non-essential amino acid, whereas glutamine is conditionally essential. Alanine is a key amino acid used for the transportation of nitrogen inside the bodies muscle structure to the liver. At the liver, the amino acid alanine is then converted to glucose. This process is called the “glucose-alanine cycle”.

Glutamine is a non-essential amino acid that holds many health benefits other than sports and recreational use. It can be used for individuals who are catabolic, malnourished, or those who are critically ill. Glutamine has shown to improve and support the bodies immune system, nitrogen balance and has shown to enhance the rate of protein synthesis.

Are there side effects of Sustamine™ use?

To date there has been NO adverse side effects reported when consuming Sustamine™ as a stand-alone product.*

As mentioned before, many brands in the supplement industry have began to use
Sustamine™ in their formulations. Some examples are USPlabs Modern BCAA+, Animal Juiced Aminos, and Betancourt Nutrition Glutamine Plus. For full nutritional panels, visit product pages to see which one is right for you and stay hydrated with Sustamine™!